DEVELOPMENT OF BILAYER TABLETS OF LOSARTAN POTASSIUM AND METFORMIN HYDROCHLORIDE LAYER USING NATURAL GUMS AS POLYMERS
نویسندگان
چکیده
منابع مشابه
Design and Evaluation of Losartan Potassium Matrix Tablets with Natural and Synthetic Polymers
The objective of the study was to formulate controlled release matrix tablets of losartan Potassium by using a combination of hydrophilic synthetic polymer like poly (ethylene oxides) and natural gums like xanthan gum, karaya gum and guar gum. A combination of synthetic hydrophobic polymers like methacrylates with synthetic hydrophilic polymer like poly (ethylene oxide) was also used in the pre...
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The present investigation reports the isolation of mucilage from Manilkara zapota seeds as per AOAC guideline and evaluating it as mucoadhesive agent. Manilkara zapota (Linn.) P. Royen syn. a small tree belonging to family sapotaceae. Physiochemical characteristics of mucilage, such as swelling index, microbial count, viscosity, hydration capacity, flow property, and pH were studied. The mucila...
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Paliperidone is a well known dopamine antagonist of the atypical antipsychotic class. In the present study Paliperidone was formulated as ER release tablets using natural and synthetic polymers separately or in combination. The aim of ER release formulation is to reduce the frequency of dosing. Tablets are prepared by direct compression method. The optimized formulations contain Paliperidone as...
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Metformin hydrochloride has relatively short plasma half-life, low absolute bioavailability. The need for the administration two to three times a day when larger doses are required can decrease patient compliance. Sustained release formulation that would maintain plasma level for 8-12 h might be sufficient for daily dosing of metformin. Sustained release products are needed for metformin to pro...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2020
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2020.v13i7.37797